1
Bcl-xL promoter is made up of two WT1 binding websites 5'-GCGGGGGAGC-3' and 5'GAGCGGGAGT-3', which might be much like the consensus WTE motif 5'-GCGTGGGAGT-3' [12] at positions -307 to -298 and -301 to -292 upstream from the transcription start off web-site of BclxL gene (Fig 5A still left). Bcl-2 promoter also includes five WT1 binding web pages with all the consensus sequence 5'-GNGNGGGNG-3' [11