Oxoline weakly activated Pgst-four::GFP and failed to activate ARE reporter expression in HepG2 cells. We found oxoline to be non-harmful to C. elegans and mammalian cells within the examined dose selection. Oxoline belongs to the class of bacteriocidal quinolone antibiotics that inhibit DNA topoisomerase exercise. Oxoline has been prescribed for remedy of urinary tract infections from gram-negati