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Eared not to be influenced. In ICU, in a retrospective study of 28 neutropenic patients who received G-CSF compared to 33 patients who did notZafrani and Azoulay BMC Infectious Diseases 2014, 14:512 http://www.biomedcentral.com/1471-2334/14/Page 6 ofreceived G-CSF, Gruson et al. did not found any difference in terms of clinical outcome and occurrence of nosocomial infections [56]. Moreover, as men
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Hose with associated bacteremia) with linezolid often used as a first-line treatment. Early reports of linezolid resistant enterococci occurred predominantly in immunocompromised hosts who resided in an ICU [68].New antifungal drugsPolyclonal intravenous immunoglobulins have been suggested to be beneficial during sepsis by modulating the immune response and neutralizing bacterial endo and exotoxin
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Hose with associated bacteremia) with linezolid often used as a first-line treatment. Early reports of linezolid resistant enterococci occurred predominantly in immunocompromised hosts who resided in an ICU [68].New antifungal drugsPolyclonal intravenous immunoglobulins have been suggested to be beneficial during sepsis by modulating the immune response and neutralizing bacterial endo and exotoxin
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Ithout malignancy [53].Non anti-infectious agentsG-CSF and GM-CSFHaemopoietic growth factors, such as granulocyte colonystimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) have been assessed in several clinical trials [54,55]. The known effect of G-CSF and GM-CSF in increasing the number of circulating neutrophil granulocytes was the rationale for clinical stud
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Ithout malignancy [53].Non anti-infectious agentsG-CSF and GM-CSFHaemopoietic growth factors, such as granulocyte colonystimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) have been assessed in several clinical trials [54,55]. The known effect of G-CSF and GM-CSF in increasing the number of circulating neutrophil granulocytes was the rationale for clinical stud
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Ing trends and recent advancesMultidrug resistant bacteriaMultidrug-resistant bacteria have become more prevalent among neutropenic patients because of their greater time exposure to the health-care environment and selective pressure from prophylactic and therapeutic antimicrobial drugs. In neutropenic patient, among Gram-negative bacteria, Pseudomonas aeruginosa, Acinetobacter species, Escherichi
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The small or large intestine is indicative of pneumatosis intestinalis. This situation refers to a necrotizing enterocolitis and can be considered as an indication for urgent surgery. Conservative management is recommended initially when these criteria are absent [50]. Badgwell et al. suggested better outcomes if it was possible to delay surgery until recovery from neutropenia [51]. General suppor
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And H4 acetylation patterns across the DES locus and surrounding 500 kb region, we next sought to obtain a more detailed map of epigenetic status specifically across the DES LCR, as this constitutes a crucial regulatory element. Chromatin used for the microarray analysis was analysed by Q-PCR to assess enrichment for selected regions within DES and the DES LCR.The ENCODE region ENr331 which spans